Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity.
Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature. 2023 Nov; 623(7989):1034-1043.
PMID: 37993715
Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation.
Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation. Mol Cell. 2022 06 02; 82(11):1992-2005.e9.
PMID: 35417664
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.
Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells. Mol Cell. 2021 09 16; 81(18):3833-3847.e11.
PMID: 34289383
?-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A.
?-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A. Mol Cell. 2019 12 19; 76(6):857-871.e9.
PMID: 31586547
Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.
Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer. Cancer Discov. 2019 06; 9(6):756-777.
PMID: 30862724
The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells.
The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells. Mol Cell. 2018 03 15; 69(6):923-937.e8.
PMID: 29547721
Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.
Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth. Cell Metab. 2017 02 07; 25(2):358-373.
PMID: 28089569
Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth.
Tetrameric Acetyl-CoA Acetyltransferase 1 Is Important for Tumor Growth. Mol Cell. 2016 12 01; 64(5):859-874.
PMID: 27867011
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation.
Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation. Nat Chem. 2015 Dec; 7(12):968-79.
PMID: 26587712
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov; 17(11):1484-96.
PMID: 26479318
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