Ryan Anderson

Research Assistant Professor
Biosciences Graduate Program Association
Publications
  1. Kulkarni A, Ibrahim S, Haider I, Basha A, Montgomery E, Ermis E, Mirmira RG, Anderson RM. A Novel 2-Hit Zebrafish Model to Study Early Pathogenesis of Non-Alcoholic Fatty Liver Disease. Biomedicines. 2022 Feb 17; 10(2). View in: PubMed

  2. Rawson A, Saxena V, Gao H, Hooks J, Xuei X, McGuire P, Hato T, Hains DS, Anderson RM, Schwaderer AL. A Pilot Single Cell Analysis of the Zebrafish Embryo Cellular Responses to Uropathogenic Escherichia coli Infection. Pathog Immun. 2022; 7(1):1-18. View in: PubMed

  3. Anderson-Baucum E, Piñeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RG. Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype. Cell Metab. 2021 09 07; 33(9):1883-1893.e7. View in: PubMed

  4. Ibrahim S, Johnson M, Stephens CH, Xu J, Moore R, Mariani A, Contreras C, Syed F, Mirmira RG, Anderson RM, Sims EK. ß-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs. Mol Metab. 2021 11; 53:101289. View in: PubMed

  5. Kulkarni A, Pineros AR, Walsh MA, Casimiro I, Ibrahim S, Hernandez-Perez M, Orr KS, Glenn L, Nadler JL, Morris MA, Tersey SA, Mirmira RG, Anderson RM. 12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes. JCI Insight. 2021 07 22; 6(14). View in: PubMed

  6. Ibrahim S, Harris-Kawano A, Haider I, Mirmira RG, Sims EK, Anderson RM. A Novel Cre-Enabled Tetracycline Inducible transgenic system for tissue specific cytokine expression in the zebrafish: CETI-PIC3. Dis Model Mech. 2020 Jan 01. View in: PubMed

  7. Hernandez-Perez M, Kulkarni A, Samala N, Sorrell C, El K, Haider I, Mukhtar Aleem A, Holman TR, Rai G, Tersey SA, Mirmira RG, Anderson RM. A 12-lipoxygenase-Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish. FASEB J. 2020 11; 34(11):14850-14862. View in: PubMed

  8. Ibrahim S, Harris-Kawano A, Haider I, Mirmira RG, Sims EK, Anderson RM. A novel Cre-enabled tetracycline-inducible transgenic system for tissue-specific cytokine expression in the zebrafish: CETI-PIC3. Dis Model Mech. 2020 06 26; 13(6). View in: PubMed

  9. Conteh AM, Reissaus CA, Hernandez-Perez M, Nakshatri S, Anderson RM, Mirmira RG, Tersey SA, Linnemann AK. Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in mouse islet ß cells. J Biol Chem. 2019 04 19; 294(16):6612-6620. View in: PubMed

  10. Kulkarni AA, Conteh AM, Sorrell CA, Mirmira A, Tersey SA, Mirmira RG, Linnemann AK, Anderson RM. An In Vivo Zebrafish Model for Interrogating ROS-Mediated Pancreatic ß-Cell Injury, Response, and Prevention. Oxid Med Cell Longev. 2018; 2018:1324739. View in: PubMed

  11. Samala N, Tersey SA, Chalasani N, Anderson RM, Mirmira RG. Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase. J Diabetes Complications. 2017 Nov; 31(11):1630-1637. View in: PubMed

  12. Hernandez-Perez M, Chopra G, Fine J, Conteh AM, Anderson RM, Linnemann AK, Benjamin C, Nelson JB, Benninger KS, Nadler JL, Maloney DJ, Tersey SA, Mirmira RG. Inhibition of 12/15-Lipoxygenase Protects Against ß-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes. Diabetes. 2017 11; 66(11):2875-2887. View in: PubMed

  13. Prince VE, Anderson RM, Dalgin G. Zebrafish Pancreas Development and Regeneration: Fishing for Diabetes Therapies. Curr Top Dev Biol. 2017; 124:235-276. View in: PubMed

  14. Han P, Bloomekatz J, Ren J, Zhang R, Grinstein JD, Zhao L, Burns CG, Burns CE, Anderson RM, Chi NC. Coordinating cardiomyocyte interactions to direct ventricular chamber morphogenesis. Nature. 2016 06 30; 534(7609):700-4. View in: PubMed

  15. Ye L, Robertson MA, Mastracci TL, Anderson RM. An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration. Dev Biol. 2016 Jan 15; 409(2):354-69. View in: PubMed

  16. Mastracci TL, Robertson MA, Mirmira RG, Anderson RM. Polyamine biosynthesis is critical for growth and differentiation of the pancreas. Sci Rep. 2015 Aug 24; 5:13269. View in: PubMed

  17. Ye L, Robertson MA, Hesselson D, Stainier DY, Anderson RM. Glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis. Development. 2015 Apr 15; 142(8):1407-17. View in: PubMed

  18. Anderson RM, Delous M, Bosch JA, Ye L, Robertson MA, Hesselson D, Stainier DY. Hepatocyte growth factor signaling in intrapancreatic ductal cells drives pancreatic morphogenesis. PLoS Genet. 2013; 9(7):e1003650. View in: PubMed

  19. Andersson O, Adams BA, Yoo D, Ellis GC, Gut P, Anderson RM, German MS, Stainier DY. Adenosine signaling promotes regeneration of pancreatic ß cells in vivo. Cell Metab. 2012 Jun 06; 15(6):885-94. View in: PubMed

  20. Luo N, West CC, Murga-Zamalloa CA, Sun L, Anderson RM, Wells CD, Weinreb RN, Travers JB, Khanna H, Sun Y. OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome. Hum Mol Genet. 2012 Aug 01; 21(15):3333-44. View in: PubMed

  21. Hugo SE, Cruz-Garcia L, Karanth S, Anderson RM, Stainier DY, Schlegel A. A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting. Genes Dev. 2012 Feb 01; 26(3):282-93. View in: PubMed

  22. Hesselson D, Anderson RM, Stainier DY. Suppression of Ptf1a activity induces acinar-to-endocrine conversion. Curr Biol. 2011 Apr 26; 21(8):712-7. View in: PubMed

  23. Tittle RK, Sze R, Ng A, Nuckels RJ, Swartz ME, Anderson RM, Bosch J, Stainier DY, Eberhart JK, Gross JM. Uhrf1 and Dnmt1 are required for development and maintenance of the zebrafish lens. Dev Biol. 2011 Feb 01; 350(1):50-63. View in: PubMed

  24. Yang YP, Anderson RM, Klingensmith J. BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning. Hum Mol Genet. 2010 Aug 01; 19(15):3030-42. View in: PubMed

  25. Kikuchi K, Holdway JE, Werdich AA, Anderson RM, Fang Y, Egnaczyk GF, Evans T, Macrae CA, Stainier DY, Poss KD. Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature. 2010 Mar 25; 464(7288):601-5. View in: PubMed

  26. Klingensmith J, Matsui M, Yang YP, Anderson RM. Roles of bone morphogenetic protein signaling and its antagonism in holoprosencephaly. Am J Med Genet C Semin Med Genet. 2010 Feb 15; 154C(1):43-51. View in: PubMed

  27. Hesselson D, Anderson RM, Beinat M, Stainier DY. Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre mediated labeling. Proc Natl Acad Sci U S A. 2009 Sep 01; 106(35):14896-901. View in: PubMed

  28. Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi NC, Shin CH, Schlegel A, Halpern M, Stainier DY. Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas development and regeneration. Dev Biol. 2009 Oct 01; 334(1):213-23. View in: PubMed

  29. Mine N, Anderson RM, Klingensmith J. BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment. Development. 2008 Aug; 135(14):2425-34. View in: PubMed

  30. Curado S, Stainier DY, Anderson RM. Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies. Nat Protoc. 2008; 3(6):948-54. View in: PubMed

  31. Curado S, Anderson RM, Jungblut B, Mumm J, Schroeter E, Stainier DY. Conditional targeted cell ablation in zebrafish: a new tool for regeneration studies. Dev Dyn. 2007 Apr; 236(4):1025-35. View in: PubMed

  32. Anderson RM, Stottmann RW, Choi M, Klingensmith J. Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival. Dev Dyn. 2006 Sep; 235(9):2507-20. View in: PubMed

  33. Bao S, Ouyang G, Bai X, Huang Z, Ma C, Liu M, Shao R, Anderson RM, Rich JN, Wang XF. Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell. 2004 Apr; 5(4):329-39. View in: PubMed

  34. Shao R, Bao S, Bai X, Blanchette C, Anderson RM, Dang T, Gishizky ML, Marks JR, Wang XF. Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression. Mol Cell Biol. 2004 May; 24(9):3992-4003. View in: PubMed

  35. Petryk A, Anderson RM, Jarcho MP, Leaf I, Carlson CS, Klingensmith J, Shawlot W, O'Connor MB. The mammalian twisted gastrulation gene functions in foregut and craniofacial development. Dev Biol. 2004 Mar 15; 267(2):374-86. View in: PubMed

  36. Anderson RM, Lawrence AR, Stottmann RW, Bachiller D, Klingensmith J. Chordin and noggin promote organizing centers of forebrain development in the mouse. Development. 2002 Nov; 129(21):4975-87. View in: PubMed