Louis Philipson

Biosciences Graduate Program Association
  1. Tosur M, Philipson LH. Precision diabetes: Lessons learned from maturity-onset diabetes of the young (MODY). J Diabetes Investig. 2022 May 31. View in: PubMed

  2. Miller KM, Kanapka LG, Rickels MR, Ahmann AJ, Aleppo G, Ang L, Bhargava A, Bode BW, Carlson A, Chaytor NS, Gannon G, Goland R, Hirsch IB, Kiblinger L, Kruger D, Kudva YC, Levy CJ, McGill JB, O'Malley G, Peters AL, Philipson LH, Philis-Tsimikas A, Pop-Busui R, Salam M, Shah VN, Thompson MJ, Vendrame F, Verdejo A, Weinstock RS, Young L, Pratley R. Benefit of Continuous Glucose Monitoring in Reducing Hypoglycemia Is Sustained Through 12 Months of Use Among Older Adults with Type 1 Diabetes. Diabetes Technol Ther. 2022 06; 24(6):424-434. View in: PubMed

  3. Witkowski P, Philipson LH, Buse JB, Robertson RP, Alejandro R, Bellin MD, Kandeel F, Baidal D, Gaglia JL, Posselt AM, Anteby R, Bachul PJ, Al-Salmay Y, Jayant K, Perez-Gutierrez A, Barth RN, Fung JJ, Ricordi C. Islets Transplantation at a Crossroads - Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the American Diabetes Association Congress. Front Endocrinol (Lausanne). 2021; 12:789526. View in: PubMed

  4. Nolan JJ, Kahkoska AR, Semnani-Azad Z, Hivert MF, Ji L, Mohan V, Eckel RH, Philipson LH, Rich SS, Gruber C, Franks PW. ADA/EASD Precision Medicine in Diabetes Initiative: An International Perspective and Future Vision for Precision Medicine in Diabetes. Diabetes Care. 2022 02 01; 45(2):261-266. View in: PubMed

  5. Bachul P, Generette GS, Perez-Gutierrez A, Borek P, Wang LJ, Golab K, Basto L, Perea L, Tibudan M, Juengel B, Kumar J, Thomas C, Philipson L, Fung J, Witkowski P. 307.5: Modified Approach Allowed for Improved Islet Allotransplantation Into Pre-vascularized Sernova Cell PouchTM Device - Preliminary Results of the Phase I/II Clinical Trial at University of Chicago. Transplantation. 2021 Dec 01; 105(12 Suppl 1):S25. View in: PubMed

  6. Haliyur R, Walker JT, Sanyoura M, Reihsmann CV, Shrestha S, Aramandla R, Poffenberger G, Ramirez AH, Redick SD, Babon JAB, Prasad N, Hegele RA, Kent SC, Harlan DM, Bottino R, Philipson LH, Brissova M, Powers AC. Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes. J Endocr Soc. 2021 Dec 01; 5(12):bvab162. View in: PubMed

  7. Alexander JT, Staab EM, Wan W, Franco M, Knitter A, Skandari MR, Bolen S, Maruthur NM, Huang ES, Philipson LH, Winn AN, Thomas CC, Zeytinoglu M, Press VG, Tung EL, Gunter K, Bindon B, Jumani S, Laiteerapong N. Longer-term Benefits and Risks of Sodium-Glucose Cotransporter-2 Inhibitors in Type 2 Diabetes: a Systematic Review and Meta-analysis. J Gen Intern Med. 2022 02; 37(2):439-448. View in: PubMed

  8. Dalgin G, Tryba AK, Cohen AP, Park SY, Philipson LH, Greeley SAW, Garcia AJ. Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes. Sci Rep. 2021 11 03; 11(1):21590. View in: PubMed

  9. Alexander JT, Staab EM, Wan W, Franco M, Knitter A, Skandari MR, Bolen S, Maruthur NM, Huang ES, Philipson LH, Winn AN, Thomas CC, Zeytinoglu M, Press VG, Tung EL, Gunter K, Bindon B, Jumani S, Laiteerapong N. The Longer-Term Benefits and Harms of Glucagon-Like Peptide-1 Receptor Agonists: a Systematic Review and Meta-Analysis. J Gen Intern Med. 2022 02; 37(2):415-438. View in: PubMed

  10. Rutsch N, Chamberlain CE, Dixon W, Spector L, Letourneau-Freiberg LR, Lwin WW, Philipson LH, Zarbock A, Saintus K, Wang J, German MS, Anderson MS, Lowell CA. Diabetes With Multiple Autoimmune and Inflammatory Conditions Linked to an Activating SKAP2 Mutation. Diabetes Care. 2021 08; 44(8):1816-1825. View in: PubMed

  11. Ryu H, Park Y, Luan H, Dalgin G, Jeffris K, Yoon HJ, Chung TS, Kim JU, Kwak SS, Lee G, Jeong H, Kim J, Bai W, Kim J, Jung YH, Tryba AK, Song JW, Huang Y, Philipson LH, Finan JD, Rogers JA. Transparent, Compliant 3D Mesostructures for Precise Evaluation of Mechanical Characteristics of Organoids. Adv Mater. 2021 Jun; 33(25):e2100026. View in: PubMed

  12. Bachul PJ, Golab K, Basto L, Zangan S, Pyda JS, Perez-Gutierrez A, Borek P, Wang LJ, Tibudan M, Tran DK, Anteby R, Generette GS, Chrzanowski J, Fendler W, Perea L, Jayant K, Lucander A, Thomas C, Philipson L, Millis JM, Fung J, Witkowski P. Post-Hoc Analysis of a Randomized, Double Blind, Prospective Study at the University of Chicago: Additional Standardizations of Trial Protocol are Needed to Evaluate the Effect of a CXCR1/2 Inhibitor in Islet Allotransplantation. Cell Transplant. 2021 Jan-Dec; 30:9636897211001774. View in: PubMed

  13. Riddle MC, Philipson LH, Rich SS, Carlsson A, Franks PW, Greeley SAW, Nolan JJ, Pearson ER, Zeitler PS, Hattersley AT. Monogenic Diabetes: From Genetic Insights to Population-Based Precision in Care. Reflections From a Diabetes Care Editors' Expert Forum. Diabetes Care. 2020 12; 43(12):3117-3128. View in: PubMed

  14. Witkowski P, Philipson LH, Kaufman DB, Ratner LE, Abouljoud MS, Bellin MD, Buse JB, Kandeel F, Stock PG, Mulligan DC, Markmann JF, Kozlowski T, Andreoni KA, Alejandro R, Baidal DA, Hardy MA, Wickrema A, Mirmira RG, Fung J, Becker YT, Josephson MA, Bachul PJ, Pyda JS, Charlton M, Millis JM, Gaglia JL, Stratta RJ, Fridell JA, Niederhaus SV, Forbes RC, Jayant K, Robertson RP, Odorico JS, Levy MF, Harland RC, Abrams PL, Olaitan OK, Kandaswamy R, Wellen JR, Japour AJ, Desai CS, Naziruddin B, Balamurugan AN, Barth RN, Ricordi C. The demise of islet allotransplantation in the United States: A call for an urgent regulatory update. Am J Transplant. 2021 04; 21(4):1365-1375. View in: PubMed

  15. Broome DT, Pantalone KM, Kashyap SR, Philipson LH. Approach to the Patient with MODY-Monogenic Diabetes. J Clin Endocrinol Metab. 2021 01 01; 106(1):237-250. View in: PubMed

  16. Herold KC, Reynolds J, Dziura J, Baidal D, Gaglia J, Gitelman SE, Gottlieb PA, Marks J, Philipson LH, Pop-Busui R, Weinstock RS. Exenatide extended release in patients with type 1 diabetes with and without residual insulin production. Diabetes Obes Metab. 2020 11; 22(11):2045-2054. View in: PubMed

  17. Chung WK, Erion K, Florez JC, Hattersley AT, Hivert MF, Lee CG, McCarthy MI, Nolan JJ, Norris JM, Pearson ER, Philipson L, McElvaine AT, Cefalu WT, Rich SS, Franks PW. Precision Medicine in Diabetes: A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2020 07; 43(7):1617-1635. View in: PubMed

  18. Chung WK, Erion K, Florez JC, Hattersley AT, Hivert MF, Lee CG, McCarthy MI, Nolan JJ, Norris JM, Pearson ER, Philipson L, McElvaine AT, Cefalu WT, Rich SS, Franks PW. Precision medicine in diabetes: a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia. 2020 09; 63(9):1671-1693. View in: PubMed

  19. Pratley RE, Kanapka LG, Rickels MR, Ahmann A, Aleppo G, Beck R, Bhargava A, Bode BW, Carlson A, Chaytor NS, Fox DS, Goland R, Hirsch IB, Kruger D, Kudva YC, Levy C, McGill JB, Peters A, Philipson L, Philis-Tsimikas A, Pop-Busui R, Shah VN, Thompson M, Vendrame F, Verdejo A, Weinstock RS, Young L, Miller KM. Effect of Continuous Glucose Monitoring on Hypoglycemia in Older Adults With Type 1 Diabetes: A Randomized Clinical Trial. JAMA. 2020 06 16; 323(23):2397-2406. View in: PubMed

  20. Dybala MP, Kuznetsov A, Motobu M, Hendren-Santiago BK, Philipson LH, Chervonsky AV, Hara M. Integrated Pancreatic Blood Flow: Bidirectional Microcirculation Between Endocrine and Exocrine Pancreas. Diabetes. 2020 07; 69(7):1439-1450. View in: PubMed

  21. Philipson LH. Harnessing heterogeneity in type 2 diabetes mellitus. Nat Rev Endocrinol. 2020 02; 16(2):79-80. View in: PubMed

  22. Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ. Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2). Diabetes. 2019 08; 68(8):1565-1576. View in: PubMed

  23. Sanyoura M, Letourneau L, Knight Johnson AE, Del Gaudio D, Greeley SAW, Philipson LH, Naylor RN. GCK-MODY in the US Monogenic Diabetes Registry: Description of 27 unpublished variants. Diabetes Res Clin Pract. 2019 May; 151:231-236. View in: PubMed

  24. Dickens LT, Letourneau LR, Sanyoura M, Greeley SAW, Philipson LH, Naylor RN. Management and pregnancy outcomes of women with GCK-MODY enrolled in the US Monogenic Diabetes Registry. Acta Diabetol. 2019 Apr; 56(4):405-411. View in: PubMed

  25. Haliyur R, Tong X, Sanyoura M, Shrestha S, Lindner J, Saunders DC, Aramandla R, Poffenberger G, Redick SD, Bottino R, Prasad N, Levy SE, Blind RD, Harlan DM, Philipson LH, Stein RW, Brissova M, Powers AC. Human islets expressing HNF1A variant have defective ß cell transcriptional regulatory networks. J Clin Invest. 2019 01 02; 129(1):246-251. View in: PubMed

  26. Feng J, Hajizadeh I, Yu X, Rashid M, Turksoy K, Samadi S, Sevil M, Hobbs N, Brandt R, Lazaro C, Maloney Z, Littlejohn E, Philipson LH, Cinar A. Multi-level Supervision and Modification of Artificial Pancreas Control System. Comput Chem Eng. 2018 Apr 06; 112:57-69. View in: PubMed

  27. Deriy LV, Gomez EA, Le BN, Philipson LH, Nelson DJ. Response to Jentsch et al. Cell Metab. 2010 Oct 06; 12(4):310. View in: PubMed

  28. Sanyoura M, Philipson LH, Naylor R. Monogenic Diabetes in Children and Adolescents: Recognition and Treatment Options. Curr Diab Rep. 2018 06 22; 18(8):58. View in: PubMed

  29. Greeley SAW, Letourneau LR, Philipson LH. Precision medicine in KCNJ11 permanent neonatal diabetes. Lancet Diabetes Endocrinol. 2018 08; 6(8):594-595. View in: PubMed

  30. Brissova M, Haliyur R, Saunders D, Shrestha S, Dai C, Blodgett DM, Bottino R, Campbell-Thompson M, Aramandla R, Poffenberger G, Lindner J, Pan FC, von Herrath MG, Greiner DL, Shultz LD, Sanyoura M, Philipson LH, Atkinson M, Harlan DM, Levy SE, Prasad N, Stein R, Powers AC. a Cell Function and Gene Expression Are Compromised in Type 1 Diabetes. Cell Rep. 2018 03 06; 22(10):2667-2676. View in: PubMed

  31. Letourneau LR, Carmody D, Philipson LH, Greeley SAW. Early Intensive Insulin Use May Preserve ß-Cell Function in Neonatal Diabetes Due to Mutations in the Proinsulin Gene. J Endocr Soc. 2018 Jan 01; 2(1):1-8. View in: PubMed

  32. Golebiewska JE, Solomina J, Thomas C, Kijek MR, Bachul PJ, Basto L, Golab K, Wang LJ, Fillman N, Tibudan M, Cieply K, Philipson L, Debska-Slizien A, Millis JM, Fung J, Witkowski P. Comparative evaluation of simple indices using a single fasting blood sample to estimate beta cell function after islet transplantation. Am J Transplant. 2018 04; 18(4):990-997. View in: PubMed

  33. Golebiewska J, Solomina J, Kijek MR, Kotukhov A, Basto L, Golab K, Bachul PJ, Konsur E, Cieply K, Fillman N, Wang LJ, Thomas CC, Philipson LH, Tibudan M, Krenc A, Debska-Slizien A, Fung J, Witkowski P. External Validation of the Newly Developed BETA-2 Scoring System for Pancreatic Islet Graft Function Assessment. Transplant Proc. 2017 Dec; 49(10):2340-2346. View in: PubMed

  34. Solomina J, Golebiewska J, Kijek MR, Kotukhov A, Bachul PJ, Basto L, Golab K, Konsur E, Cieply K, Fillman N, Wang LJ, Thomas CC, Philipson LH, Tibudan M, Debska-Slizien A, Fung J, Gelrud A, Matthews JB, Witkowski P. Pain Control, Glucose Control, and Quality of Life in Patients With Chronic Pancreatitis After Total Pancreatectomy With Islet Autotransplantation: A Preliminary Report. Transplant Proc. 2017 Dec; 49(10):2333-2339. View in: PubMed

  35. Hwang JL, Park SY, Ye H, Sanyoura M, Pastore AN, Carmody D, Del Gaudio D, Wilson JF, Hanis CL, Liu X, Atzmon G, Glaser B, Philipson LH, Greeley SAW. FOXP3 mutations causing early-onset insulin-requiring diabetes but without other features of immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome. Pediatr Diabetes. 2018 05; 19(3):388-392. View in: PubMed

  36. Vierra NC, Dickerson MT, Philipson LH, Jacobson DA. Simultaneous Real-Time Measurement of the ß-Cell Membrane Potential and Ca2+ Influx to Assess the Role of Potassium Channels on ß-Cell Function. Methods Mol Biol. 2018; 1684:73-84. View in: PubMed

  37. Bergeron V, Ghislain J, Vivot K, Tamarina N, Philipson LH, Fielitz J, Poitout V. Deletion of Protein Kinase D1 in Pancreatic ß-Cells Impairs Insulin Secretion in High-Fat Diet-Fed Mice. Diabetes. 2018 01; 67(1):71-77. View in: PubMed

  38. Sanyoura M, Jacobsen L, Carmody D, Del Gaudio D, Alkorta-Aranburu G, Arndt K, Hu Y, Kobiernicki F, Kusmartseva I, Atkinson MA, Philipson LH, Schatz D, Campbell-Thompson M, Greeley SAW. Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA. J Clin Endocrinol Metab. 2018 01 01; 103(1):35-45. View in: PubMed

  39. Letourneau LR, Carmody D, Wroblewski K, Denson AM, Sanyoura M, Naylor RN, Philipson LH, Greeley SAW. Diabetes Presentation in Infancy: High Risk of Diabetic Ketoacidosis. Diabetes Care. 2017 10; 40(10):e147-e148. View in: PubMed

  40. Huynh T, Daddysman MK, Bao Y, Selewa A, Kuznetsov A, Philipson LH, Scherer NF. Correlative imaging across microscopy platforms using the fast and accurate relocation of microscopic experimental regions (FARMER) method. Rev Sci Instrum. 2017 May; 88(5):053702. View in: PubMed

  41. Greeley SA, Zielinski MC, Poudel A, Ye H, Berry S, Taxy JB, Carmody D, Steiner DF, Philipson LH, Wood JR, Hara M. Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes. J Clin Endocrinol Metab. 2017 01 01; 102(1):1-5. View in: PubMed

  42. Tekin Z, Garfinkel MR, Chon WJ, Schenck L, Golab K, Savari O, Thistlethwaite JR, Philipson LH, Majewski C, Pannain S, Ramachandran S, Rezania K, Hariprasad SM, Millis JM, Witkowski P. Outcomes of Pancreatic Islet Allotransplantation Using the Edmonton Protocol at the University of Chicago. Transplant Direct. 2016 Oct; 2(10):e105. View in: PubMed

  43. Fridlyand LE, Tamarina NA, Schally AV, Philipson LH. Growth Hormone-Releasing Hormone in Diabetes. Front Endocrinol (Lausanne). 2016; 7:129. View in: PubMed

  44. Carmody D, Pastore AN, Landmeier KA, Letourneau LR, Martin R, Hwang JL, Naylor RN, Hunter SJ, Msall ME, Philipson LH, Scott MN, Greeley SA. Patients with KCNJ11-related diabetes frequently have neuropsychological impairments compared with sibling controls. Diabet Med. 2016 10; 33(10):1380-6. View in: PubMed

  45. Rosario W, Singh I, Wautlet A, Patterson C, Flak J, Becker TC, Ali A, Tamarina N, Philipson LH, Enquist LW, Myers MG, Rhodes CJ. The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions. Diabetes. 2016 09; 65(9):2711-23. View in: PubMed

  46. Fridlyand LE, Philipson LH. Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis. PLoS One. 2016; 11(5):e0152869. View in: PubMed

  47. Carmody D, Naylor RN, Bell CD, Berry S, Montgomery JT, Tadie EC, Hwang JL, Greeley SA, Philipson LH. GCK-MODY in the US National Monogenic Diabetes Registry: frequently misdiagnosed and unnecessarily treated. Acta Diabetol. 2016 Oct; 53(5):703-8. View in: PubMed

  48. Yi Y, Sun X, Gibson-Corley K, Xie W, Liang B, He N, Tyler SR, Uc A, Philipson LH, Wang K, Hara M, Ode KL, Norris AW, Engelhardt JF. A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling. Endocrinology. 2016 05; 157(5):1852-65. View in: PubMed

  49. Hara M, Fowler JL, Bell GI, Philipson LH. Resting beta-cells - A functional reserve? Diabetes Metab. 2016 Jun; 42(3):157-61. View in: PubMed

  50. Campbell JE, Ussher JR, Mulvihill EE, Kolic J, Baggio LL, Cao X, Liu Y, Lamont BJ, Morii T, Streutker CJ, Tamarina N, Philipson LH, Wrana JL, MacDonald PE, Drucker DJ. TCF1 links GIPR signaling to the control of beta cell function and survival. Nat Med. 2016 Jan; 22(1):84-90. View in: PubMed

  51. Oropeza D, Jouvet N, Bouyakdan K, Perron G, Ringuette LJ, Philipson LH, Kiss RS, Poitout V, Alquier T, Estall JL. PGC-1 coactivators in ß-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids. Mol Metab. 2015 Nov; 4(11):811-22. View in: PubMed

  52. Koshy AA, Gordon IO, Van Ha TG, Kaplan EL, Philipson LH. Metastatic Insulinoma Following Resection of Nonsecreting Pancreatic Islet Cell Tumor: A Case Report and Review of the Literature. J Investig Med High Impact Case Rep. 2013 Jan-Mar; 1(1):2324709612473274. View in: PubMed

  53. Fan F, Ji C, Wu Y, Ferguson SM, Tamarina N, Philipson LH, Lou X. Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis. J Clin Invest. 2015 Nov 02; 125(11):4026-41. View in: PubMed

  54. Perrone ME, Carmody D, Philipson LH, Greeley SA. An online monogenic diabetes discussion group: supporting families and fueling new research. Transl Res. 2015 Nov; 166(5):425-31. View in: PubMed

  55. Swisa A, Granot Z, Tamarina N, Sayers S, Bardeesy N, Philipson L, Hodson DJ, Wikstrom JD, Rutter GA, Leibowitz G, Glaser B, Dor Y. Loss of Liver Kinase B1 (LKB1) in Beta Cells Enhances Glucose-stimulated Insulin Secretion Despite Profound Mitochondrial Defects. J Biol Chem. 2015 Aug 21; 290(34):20934-20946. View in: PubMed

  56. Carmody D, Park SY, Ye H, Perrone ME, Alkorta-Aranburu G, Highland HM, Hanis CL, Philipson LH, Bell GI, Greeley SA. Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism. J Med Genet. 2015 Sep; 52(9):612-6. View in: PubMed

  57. Carmody D, Naylor RN, Philipson LH. Insulin dosing in pediatric diabetic ketoacidosis: where to start? JAMA. 2015 Jun 09; 313(22):2274-5. View in: PubMed

  58. Carmody D, Beca FA, Bell CD, Hwang JL, Dickens JT, Devine NA, Mackay DJ, Temple IK, Hays LR, Naylor RN, Philipson LH, Greeley SA. Role of noninsulin therapies alone or in combination in chromosome 6q24-related transient neonatal diabetes: sulfonylurea improves but does not always normalize insulin secretion. Diabetes Care. 2015 Jun; 38(6):e86-7. View in: PubMed

  59. Thurber BW, Carmody D, Tadie EC, Pastore AN, Dickens JT, Wroblewski KE, Naylor RN, Philipson LH, Greeley SA. Age at the time of sulfonylurea initiation influences treatment outcomes in KCNJ11-related neonatal diabetes. Diabetologia. 2015 Jul; 58(7):1430-5. View in: PubMed

  60. Rajan S, Dickson LM, Mathew E, Orr CM, Ellenbroek JH, Philipson LH, Wicksteed B. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic ß-cells via protein kinase A. Mol Metab. 2015 Apr; 4(4):265-76. View in: PubMed

  61. Ducat L, Rubenstein A, Philipson LH, Anderson BJ. A review of the mental health issues of diabetes conference. Diabetes Care. 2015 Feb; 38(2):333-8. View in: PubMed

  62. Philipson LH, Bell G, Polonsky KS. Donald F. Steiner MD, 1930-2014: discoverer of proinsulin. Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4):940-1. View in: PubMed

  63. Ducat LJ, Philipson LH, Anderson BJ. Routine depression screening for patients with diabetes--reply. JAMA. 2014 Dec 10; 312(22):2413. View in: PubMed

  64. Thomas CC, Philipson LH. Update on diabetes classification. Med Clin North Am. 2015 Jan; 99(1):1-16. View in: PubMed

  65. Kim K, Oh CM, Ohara-Imaizumi M, Park S, Namkung J, Yadav VK, Tamarina NA, Roe MW, Philipson LH, Karsenty G, Nagamatsu S, German MS, Kim H. Functional role of serotonin in insulin secretion in a diet-induced insulin-resistant state. Endocrinology. 2015 Feb; 156(2):444-52. View in: PubMed

  66. Uhlén M, Lindberg M, Philipson L. The gene for staphylococcal protein A. Immunol Today. 1984 Aug; 5(8):244-8. View in: PubMed

  67. Carmody D, Bell CD, Hwang JL, Dickens JT, Sima DI, Felipe DL, Zimmer CA, Davis AO, Kotlyarevska K, Naylor RN, Philipson LH, Greeley SA. Sulfonylurea treatment before genetic testing in neonatal diabetes: pros and cons. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2709-14. View in: PubMed

  68. Ducat L, Philipson LH, Anderson BJ. The mental health comorbidities of diabetes. JAMA. 2014 Aug 20; 312(7):691-2. View in: PubMed

  69. Eames SC, Kinkel MD, Rajan S, Prince VE, Philipson LH. Transgenic zebrafish model of the C43G human insulin gene mutation. J Diabetes Investig. 2013 Mar 18; 4(2):157-67. View in: PubMed

  70. Naylor RN, Greeley SA, Bell GI, Philipson LH. Genetics and pathophysiology of neonatal diabetes mellitus. J Diabetes Investig. 2011 Jun 05; 2(3):158-69. View in: PubMed

  71. Liew CW, Assmann A, Templin AT, Raum JC, Lipson KL, Rajan S, Qiang G, Hu J, Kawamori D, Lindberg I, Philipson LH, Sonenberg N, Goldfine AB, Stoffers DA, Mirmira RG, Urano F, Kulkarni RN. Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic ß cells. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):E2319-28. View in: PubMed

  72. Smith EP, An Z, Wagner C, Lewis AG, Cohen EB, Li B, Mahbod P, Sandoval D, Perez-Tilve D, Tamarina N, Philipson LH, Stoffers DA, Seeley RJ, D'Alessio DA. The role of ß cell glucagon-like peptide-1 signaling in glucose regulation and response to diabetes drugs. Cell Metab. 2014 Jun 03; 19(6):1050-7. View in: PubMed

  73. Carmody D, Philipson L. Neonatal diabetes: the brain comes into focus. Lancet Diabetes Endocrinol. 2013 Nov; 1(3):167-8. View in: PubMed

  74. Sui H, Yi Y, Yao J, Liang B, Sun X, Hu S, Uc A, Nelson DJ, Ode KL, Philipson LH, Engelhardt JF, Norris AW. Quantifying insulin sensitivity and entero-insular responsiveness to hyper- and hypoglycemia in ferrets. PLoS One. 2014; 9(3):e90519. View in: PubMed

  75. Coleman NJ, Miernik J, Philipson L, Fogelfeld L. Lean versus obese diabetes mellitus patients in the United States minority population. J Diabetes Complications. 2014 Jul-Aug; 28(4):500-5. View in: PubMed

  76. Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y. Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in ß cells. Cell Metab. 2014 Jan 07; 19(1):109-21. View in: PubMed

  77. Park SY, Ludwig MZ, Tamarina NA, He BZ, Carl SH, Dickerson DA, Barse L, Arun B, Williams CL, Miles CM, Philipson LH, Steiner DF, Bell GI, Kreitman M. Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 2014 Feb; 196(2):539-55. View in: PubMed

  78. Burov S, Tabei SM, Huynh T, Murrell MP, Philipson LH, Rice SA, Gardel ML, Scherer NF, Dinner AR. Distribution of directional change as a signature of complex dynamics. Proc Natl Acad Sci U S A. 2013 Dec 03; 110(49):19689-94. View in: PubMed

  79. Shalev SA, Tenenbaum-Rakover Y, Horovitz Y, Paz VP, Ye H, Carmody D, Highland HM, Boerwinkle E, Hanis CL, Muzny DM, Gibbs RA, Bell GI, Philipson LH, Greeley SA. Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder. Pediatr Diabetes. 2014 May; 15(3):252-6. View in: PubMed

  80. Naylor RN, John PM, Winn AN, Carmody D, Greeley SA, Philipson LH, Bell GI, Huang ES. Cost-effectiveness of MODY genetic testing: translating genomic advances into practical health applications. Diabetes Care. 2014; 37(1):202-9. View in: PubMed

  81. Fridlyand LE, Jacobson DA, Philipson LH. Ion channels and regulation of insulin secretion in human ß-cells: a computational systems analysis. Islets. 2013 Jan-Feb; 5(1):1-15. View in: PubMed

  82. Tabei SM, Burov S, Kim HY, Kuznetsov A, Huynh T, Jureller J, Philipson LH, Dinner AR, Scherer NF. Intracellular transport of insulin granules is a subordinated random walk. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):4911-6. View in: PubMed

  83. Torres JM, Cox NJ, Philipson LH. Genome wide association studies for diabetes: perspective on results and challenges. Pediatr Diabetes. 2013 Mar; 14(2):90-6. View in: PubMed

  84. Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B. ß-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion. Diabetes. 2013 May; 62(5):1527-36. View in: PubMed

  85. Fridlyand LE, Philipson LH. A computational systems analysis of factors regulating a cell glucagon secretion. Islets. 2012 Jul-Aug; 4(4):262-83. View in: PubMed

  86. Rajan S, Torres J, Thompson MS, Philipson LH. SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion. Am J Physiol Endocrinol Metab. 2012 Mar 15; 302(6):E714-23. View in: PubMed

  87. Greeley SA, Naylor RN, Philipson LH, Bell GI. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Curr Diab Rep. 2011 Dec; 11(6):519-32. View in: PubMed

  88. Fridlyand LE, Philipson LH. Coupling of metabolic, second messenger pathways and insulin granule dynamics in pancreatic beta-cells: a computational analysis. Prog Biophys Mol Biol. 2011 Nov; 107(2):293-303. View in: PubMed

  89. Greeley SA, Naylor RN, Cook LS, Tucker SE, Lipton RB, Philipson LH. Creation of the Web-based University of Chicago Monogenic Diabetes Registry: using technology to facilitate longitudinal study of rare subtypes of diabetes. J Diabetes Sci Technol. 2011 Jul 01; 5(4):879-86. View in: PubMed

  90. Naylor R, Philipson LH. Who should have genetic testing for maturity-onset diabetes of the young? Clin Endocrinol (Oxf). 2011 Oct; 75(4):422-6. View in: PubMed

  91. Greeley SA, John PM, Winn AN, Ornelas J, Lipton RB, Philipson LH, Bell GI, Huang ES. The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes. Diabetes Care. 2011 Mar; 34(3):622-7. View in: PubMed

  92. Støy J, Steiner DF, Park SY, Ye H, Philipson LH, Bell GI. Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene. Rev Endocr Metab Disord. 2010 Sep; 11(3):205-15. View in: PubMed

  93. Kinkel MD, Eames SC, Philipson LH, Prince VE. Intraperitoneal injection into adult zebrafish. J Vis Exp. 2010 Aug 30; (42). View in: PubMed

  94. Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG, Gannon M, Powers AC, Dempsey PJ. Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Diabetes. 2010 Dec; 59(12):3090-8. View in: PubMed

  95. Lopez JP, Turner JR, Philipson LH. Glucose-induced ERM protein activation and translocation regulates insulin secretion. Am J Physiol Endocrinol Metab. 2010 Nov; 299(5):E772-85. View in: PubMed

  96. Jacobson DA, Mendez F, Thompson M, Torres J, Cochet O, Philipson LH. Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses. J Physiol. 2010 Sep 15; 588(Pt 18):3525-37. View in: PubMed

  97. Fridlyand LE, Tamarina N, Philipson LH. Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms. Am J Physiol Endocrinol Metab. 2010 Oct; 299(4):E517-32. View in: PubMed

  98. Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J. Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature. 2010 Jul 29; 466(7306):627-31. View in: PubMed

  99. Eames SC, Philipson LH, Prince VE, Kinkel MD. Blood sugar measurement in zebrafish reveals dynamics of glucose homeostasis. Zebrafish. 2010 Jun; 7(2):205-13. View in: PubMed

  100. Fridlyand LE, Philipson LH. Glucose sensing in the pancreatic beta cell: a computational systems analysis. Theor Biol Med Model. 2010 May 24; 7:15. View in: PubMed

  101. Greeley SA, Tucker SE, Naylor RN, Bell GI, Philipson LH. Neonatal diabetes mellitus: a model for personalized medicine. Trends Endocrinol Metab. 2010 Aug; 21(8):464-72. View in: PubMed

  102. Greeley SA, Tucker SE, Worrell HI, Skowron KB, Bell GI, Philipson LH. Update in neonatal diabetes. Curr Opin Endocrinol Diabetes Obes. 2010 Feb; 17(1):13-9. View in: PubMed

  103. Rajan S, Eames SC, Park SY, Labno C, Bell GI, Prince VE, Philipson LH. In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes. Am J Physiol Endocrinol Metab. 2010 Mar; 298(3):E403-10. View in: PubMed

  104. Steiner DF, Park SY, Støy J, Philipson LH, Bell GI. A brief perspective on insulin production. Diabetes Obes Metab. 2009 Nov; 11 Suppl 4:189-96. View in: PubMed

  105. Deriy LV, Gomez EA, Jacobson DA, Wang X, Hopson JA, Liu XY, Zhang G, Bindokas VP, Philipson LH, Nelson DJ. The granular chloride channel ClC-3 is permissive for insulin secretion. Cell Metab. 2009 Oct; 10(4):316-23. View in: PubMed

  106. Gimi B, Kwon J, Kuznetsov A, Vachha B, Magin RL, Philipson LH, Lee JB. A nanoporous, transparent microcontainer for encapsulated islet therapy. J Diabetes Sci Technol. 2009 Mar; 3(2):297-303. View in: PubMed

  107. Kumaraguru J, Flanagan SE, Greeley SA, Nuboer R, Støy J, Philipson LH, Hattersley AT, Rubio-Cabezas O. Tooth discoloration in patients with neonatal diabetes after transfer onto glibenclamide: a previously unreported side effect. Diabetes Care. 2009 Aug; 32(8):1428-30. View in: PubMed

  108. Fridlyand LE, Jacobson DA, Kuznetsov A, Philipson LH. A model of action potentials and fast Ca2+ dynamics in pancreatic beta-cells. Biophys J. 2009 Apr 22; 96(8):3126-39. View in: PubMed

  109. Chen WS, Peng XD, Wang Y, Xu PZ, Chen ML, Luo Y, Jeon SM, Coleman K, Haschek WM, Bass J, Philipson LH, Hay N. Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice. Mol Cell Biol. 2009 Jun; 29(11):3151-62. View in: PubMed

  110. Jacobson DA, Wicksteed BL, Philipson LH. The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing. Diabetes. 2009 Feb; 58(2):304-6. View in: PubMed

  111. Chen D, Du W, Liu Y, Liu W, Kuznetsov A, Mendez FE, Philipson LH, Ismagilov RF. The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):16843-8. View in: PubMed

  112. Støy J, Greeley SA, Paz VP, Ye H, Pastore AN, Skowron KB, Lipton RB, Cogen FR, Bell GI, Philipson LH. Diagnosis and treatment of neonatal diabetes: a United States experience. Pediatr Diabetes. 2008 Oct; 9(5):450-9. View in: PubMed

  113. Tamarina NA, Kuznetsov A, Philipson LH. Reversible translocation of EYFP-tagged STIM1 is coupled to calcium influx in insulin secreting beta-cells. Cell Calcium. 2008 Dec; 44(6):533-44. View in: PubMed

  114. Philipson LH, Roe MW. When BAD is good for beta cells. Cell Metab. 2008 Apr; 7(4):280-1. View in: PubMed

  115. Freimuth P, Philipson L, Carson SD. The coxsackievirus and adenovirus receptor. Curr Top Microbiol Immunol. 2008; 323:67-87. View in: PubMed

  116. Fridlyand LE, Philipson LH. Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis. Curr Diabetes Rev. 2006 May; 2(2):241-59. View in: PubMed

  117. Adair B, Nunn R, Lewis S, Dukes I, Philipson L, Yeager M. Single particle image reconstruction of the human recombinant Kv2.1 channel. Biophys J. 2008 Mar 15; 94(6):2106-14. View in: PubMed

  118. Molven A, Ringdal M, Nordbø AM, Raeder H, Støy J, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, Undlien DE, Joner G, Søvik O. Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes. 2008 Apr; 57(4):1131-5. View in: PubMed

  119. Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Støy J, Steiner DF, Philipson LH, Bell GI. Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes. 2008 Apr; 57(4):1034-42. View in: PubMed

  120. Fridlyand LE, Harbeck MC, Roe MW, Philipson LH. Regulation of cAMP dynamics by Ca2+ and G protein-coupled receptors in the pancreatic beta-cell: a computational approach. Am J Physiol Cell Physiol. 2007 Dec; 293(6):C1924-33. View in: PubMed

  121. Jacobson DA, Philipson LH. Action potentials and insulin secretion: new insights into the role of Kv channels. Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:89-98. View in: PubMed

  122. Bao S, Jacobson DA, Wohltmann M, Bohrer A, Jin W, Philipson LH, Turk J. Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice. Am J Physiol Endocrinol Metab. 2008 Feb; 294(2):E217-29. View in: PubMed

  123. Støy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SA, Patch AM, Ellard S, Steiner DF, Hattersley AT, Philipson LH, Bell GI. Insulin gene mutations as a cause of permanent neonatal diabetes. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):15040-4. View in: PubMed

  124. Jacobson DA, Kuznetsov A, Lopez JP, Kash S, Ammälä CE, Philipson LH. Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion. Cell Metab. 2007 Sep; 6(3):229-35. View in: PubMed

  125. Ross LF, Philipson LH. Ethics of hematopoietic stem cell transplantation in type 1 diabetes mellitus. JAMA. 2007 Jul 18; 298(3):285; author reply 285-6. View in: PubMed

  126. Kitiphongspattana K, Khan TA, Ishii-Schrade K, Roe MW, Philipson LH, Gaskins HR. Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells. Am J Physiol Endocrinol Metab. 2007 Jun; 292(6):E1543-54. View in: PubMed

  127. Jacobson DA, Philipson LH. TRP channels of the pancreatic beta cell. Handb Exp Pharmacol. 2007; (179):409-24. View in: PubMed

  128. Jacobson DA, Weber CR, Bao S, Turk J, Philipson LH. Modulation of the pancreatic islet beta-cell-delayed rectifier potassium channel Kv2.1 by the polyunsaturated fatty acid arachidonate. J Biol Chem. 2007 Mar 09; 282(10):7442-9. View in: PubMed

  129. Yin D, Tao J, Lee DD, Shen J, Hara M, Lopez J, Kuznetsov A, Philipson LH, Chong AS. Recovery of islet beta-cell function in streptozotocin- induced diabetic mice: an indirect role for the spleen. Diabetes. 2006 Dec; 55(12):3256-63. View in: PubMed

  130. Avila JG, Wang Y, Barbaro B, Gangemi A, Qi M, Kuechle J, Doubleday N, Doubleday M, Churchill T, Salehi P, Shapiro J, Philipson LH, Benedetti E, Lakey JR, Oberholzer J. Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier. Am J Transplant. 2006 Dec; 6(12):2861-70. View in: PubMed

  131. Fridlyand LE, Philipson LH. Cold climate genes and the prevalence of type 2 diabetes mellitus. Med Hypotheses. 2006; 67(5):1034-41. View in: PubMed

  132. Roe MW, Fiekers JF, Philipson LH, Bindokas VP. Visualizing calcium signaling in cells by digitized wide-field and confocal fluorescent microscopy. Methods Mol Biol. 2006; 319:37-66. View in: PubMed

  133. Gimi B, Leoni L, Oberholzer J, Braun M, Avila J, Wang Y, Desai T, Philipson LH, Magin RL, Roman BB. Functional MR microimaging of pancreatic beta-cell activation. Cell Transplant. 2006; 15(2):195-203. View in: PubMed

  134. Jacobson DA, Cho J, Landa LR, Tamarina NA, Roe MW, Buxbaum JD, Philipson LH. Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression. Am J Physiol Endocrinol Metab. 2006 Sep; 291(3):E587-95. View in: PubMed

  135. Woo YH. The Compton Effect and Tertiary X-Radiation. Proc Natl Acad Sci U S A. 1925 Feb; 11(2):123-5. View in: PubMed

  136. Compton AH, Woo YH. The Wave-Length of Molybdenum K(alpha) Rays when Scattered by Light Elements. Proc Natl Acad Sci U S A. 1924 Jun; 10(6):271-3. View in: PubMed

  137. Woo YH. Note on Absorption Measurements of the X-Rays Reflected from a Calcite Crystal. Proc Natl Acad Sci U S A. 1924 Apr; 10(4):145-8. View in: PubMed

  138. Chong AS, Shen J, Tao J, Yin D, Kuznetsov A, Hara M, Philipson LH. Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration. Science. 2006 Mar 24; 311(5768):1774-5. View in: PubMed

  139. Fridlyand LE, Philipson LH. Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches. Ann N Y Acad Sci. 2005 Dec; 1066:136-51. View in: PubMed

  140. Fridlyand LE, Philipson LH. Reactive species and early manifestation of insulin resistance in type 2 diabetes. Diabetes Obes Metab. 2006 Mar; 8(2):136-45. View in: PubMed

  141. Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH. Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes. 2005 Nov; 54(11):3073-81. View in: PubMed

  142. Tamarina NA, Kuznetsov A, Fridlyand LE, Philipson LH. Delayed-rectifier (KV2.1) regulation of pancreatic beta-cell calcium responses to glucose: inhibitor specificity and modeling. Am J Physiol Endocrinol Metab. 2005 Oct; 289(4):E578-85. View in: PubMed

  143. Fridlyand LE, Ma L, Philipson LH. Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions. Am J Physiol Endocrinol Metab. 2005 Nov; 289(5):E839-48. View in: PubMed

  144. Wang CZ, Wang Y, Di A, Magnuson MA, Ye H, Roe MW, Nelson DJ, Bell GI, Philipson LH. 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways. Biochem Biophys Res Commun. 2005 May 20; 330(4):1073-9. View in: PubMed

  145. Hays LB, Wicksteed B, Wang Y, McCuaig JF, Philipson LH, Edwardson JM, Rhodes CJ. Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells. J Endocrinol. 2005 Apr; 185(1):57-67. View in: PubMed

  146. Kuznetsov A, Bindokas VP, Marks JD, Philipson LH. FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets. Am J Physiol Cell Physiol. 2005 Jul; 289(1):C224-9. View in: PubMed

  147. Fridlyand LE, Philipson LH. Does the glucose-dependent insulin secretion mechanism itself cause oxidative stress in pancreatic beta-cells? Diabetes. 2004 Aug; 53(8):1942-8. View in: PubMed

  148. Ma L, Bindokas VP, Kuznetsov A, Rhodes C, Hays L, Edwardson JM, Ueda K, Steiner DF, Philipson LH. Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9266-71. View in: PubMed

  149. Garfinkel MR, Connors M, Ostrega D, Jarosz J, Philipson L, Millis JM. Islet isolation under cGMP conditions: replacing the coil. Transplant Proc. 2004 May; 36(4):1031-3. View in: PubMed

  150. OLDING L, PHILIPSON L. Two cases of listeriosis in the newborn, associated with placental infection. Acta Pathol Microbiol Scand. 1960; 48:24-30. View in: PubMed

  151. OBERG B, BENGTSSON S, PHILIPSON L. GEL FILTRATION OF NUCLEIC ACIDS ON PEARL-CONDENSED AGAROSE. Biochem Biophys Res Commun. 1965 Jun 18; 20:36-40. View in: PubMed

  152. PHILIPSON L, ZETTERQVIST O. THE PRESENCE OF DNA IN HUMAN ERYTHROCYTE MEMBRANES. Biochim Biophys Acta. 1964 Sep 11; 91:171-3. View in: PubMed

  153. PHILIPSON L, LIND M. ENTEROVIRUS ECLIPSE IN A CELL-FREE SYSTEM. Virology. 1964 Jul; 23:322-32. View in: PubMed

  154. BENGTSSON S, PHILIPSON L. CHROMATOGRAPHY OF ANIMAL VIRUSES ON PEARL-CONDENSED AGAR. Biochim Biophys Acta. 1964 Mar 30; 79:399-406. View in: PubMed

  155. PHILIPSON L. THE EARLY INTERACTION OF ANIMAL VIRUSES AND CELLS. Prog Med Virol. 1963; 5:43-78. View in: PubMed

  156. HERMODSSON S, PHILIPSON L. A SENSITIVE METHOD FOR INTERFERON ASSAY. Proc Soc Exp Biol Med. 1963 Dec; 114:574-9. View in: PubMed

  157. BENGTSSON S, PHILIPSON L, ALBERTSSON PA. Countercurrent distribution of polio virus. Biochem Biophys Res Commun. 1962 Oct 31; 9:318-22. View in: PubMed

  158. ALBERTSSON PA, PHILIPSON L. Antigen-antibody in liquid two-phase systems: a method for studying immunological reactions. Nature. 1960 Jan 02; 185:38-40. View in: PubMed

  159. Tamarina NA, Wang Y, Mariotto L, Kuznetsov A, Bond C, Adelman J, Philipson LH. Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses. Diabetes. 2003 Aug; 52(8):2000-6. View in: PubMed

  160. Ueda K, Lipkind GM, Zhou A, Zhu X, Kuznetsov A, Philipson L, Gardner P, Zhang C, Steiner DF. Mutational analysis of predicted interactions between the catalytic and P domains of prohormone convertase 3 (PC3/PC1). Proc Natl Acad Sci U S A. 2003 May 13; 100(10):5622-7. View in: PubMed

  161. Fridlyand LE, Tamarina N, Philipson LH. Modeling of Ca2+ flux in pancreatic beta-cells: role of the plasma membrane and intracellular stores. Am J Physiol Endocrinol Metab. 2003 Jul; 285(1):E138-54. View in: PubMed

  162. Bindokas VP, Kuznetsov A, Sreenan S, Polonsky KS, Roe MW, Philipson LH. Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem. 2003 Mar 14; 278(11):9796-801. View in: PubMed

  163. Yaekura K, Julyan R, Wicksteed BL, Hays LB, Alarcon C, Sommers S, Poitout V, Baskin DG, Wang Y, Philipson LH, Rhodes CJ. Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem. 2003 Mar 14; 278(11):9715-21. View in: PubMed

  164. Philipson LH. beta-Agonists and metabolism. J Allergy Clin Immunol. 2002 Dec; 110(6 Suppl):S313-7. View in: PubMed

  165. Loskog A, Hedlund T, Wester K, de la Torre M, Philipson L, Malmström PU, Tötterman TH. Human urinary bladder carcinomas express adenovirus attachment and internalization receptors. Gene Ther. 2002 May; 9(9):547-53. View in: PubMed

  166. Qian F, Huang P, Ma L, Kuznetsov A, Tamarina N, Philipson LH. TRP genes: candidates for nonselective cation channels and store-operated channels in insulin-secreting cells. Diabetes. 2002 Feb; 51 Suppl 1:S183-9. View in: PubMed

  167. Shih DQ, Screenan S, Munoz KN, Philipson L, Pontoglio M, Yaniv M, Polonsky KS, Stoffel M. Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. Diabetes. 2001 Nov; 50(11):2472-80. View in: PubMed

  168. Tallone T, Malin S, Samuelsson A, Wilbertz J, Miyahara M, Okamoto K, Poellinger L, Philipson L, Pettersson S. A mouse model for adenovirus gene delivery. Proc Natl Acad Sci U S A. 2001 Jul 03; 98(14):7910-5. View in: PubMed

  169. Ma L, Tamarina N, Wang Y, Kuznetsov A, Patel N, Kending C, Hering BJ, Philipson LH. Baculovirus-mediated gene transfer into pancreatic islet cells. Diabetes. 2000 Dec; 49(12):1986-91. View in: PubMed

  170. Wilson SM, Toth PT, Oh SB, Gillard SE, Volsen S, Ren D, Philipson LH, Lee EC, Fletcher CF, Tessarollo L, Copeland NG, Jenkins NA, Miller RJ. The status of voltage-dependent calcium channels in alpha 1E knock-out mice. J Neurosci. 2000 Dec 01; 20(23):8566-71. View in: PubMed

  171. Raho G, Barone V, Rossi D, Philipson L, Sorrentino V. The gas 5 gene shows four alternative splicing patterns without coding for a protein. Gene. 2000 Oct 03; 256(1-2):13-7. View in: PubMed

  172. Tomko RP, Johansson CB, Totrov M, Abagyan R, Frisén J, Philipson L. Expression of the adenovirus receptor and its interaction with the fiber knob. Exp Cell Res. 2000 Feb 25; 255(1):47-55. View in: PubMed

  173. Zhou YP, Pena JC, Roe MW, Mittal A, Levisetti M, Baldwin AC, Pugh W, Ostrega D, Ahmed N, Bindokas VP, Philipson LH, Hanahan D, Thompson CB, Polonsky KS. Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. Am J Physiol Endocrinol Metab. 2000 Feb; 278(2):E340-51. View in: PubMed

  174. Philipson LH. Beta-cell ion channels: keys to endodermal excitability. Horm Metab Res. 1999 Aug; 31(8):455-61. View in: PubMed

  175. Sariola H, Philipson L. Bridge over troubled waters. Nat Med. 1999 Jan; 5(1):22-3. View in: PubMed

  176. Dukes ID, Sreenan S, Roe MW, Levisetti M, Zhou YP, Ostrega D, Bell GI, Pontoglio M, Yaniv M, Philipson L, Polonsky KS. Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice. J Biol Chem. 1998 Sep 18; 273(38):24457-64. View in: PubMed

  177. Philipson L. Cell cycle exit: growth arrest, apoptosis, and tumor suppression revisited. Mol Med. 1998 Apr; 4(4):205-13. View in: PubMed

  178. Roe MW, Worley JF, Qian F, Tamarina N, Mittal AA, Dralyuk F, Blair NT, Mertz RJ, Philipson LH, Dukes ID. Characterization of a Ca2+ release-activated nonselective cation current regulating membrane potential and [Ca2+]i oscillations in transgenically derived beta-cells. J Biol Chem. 1998 Apr 24; 273(17):10402-10. View in: PubMed

  179. Zhou YP, Teng D, Dralyuk F, Ostrega D, Roe MW, Philipson L, Polonsky KS. Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. J Clin Invest. 1998 Apr 15; 101(8):1623-32. View in: PubMed

  180. Sun L, Philipson LH, Miller RJ. Regulation of K+ and Ca++ channels by a family of neuropeptide Y receptors. J Pharmacol Exp Ther. 1998 Feb; 284(2):625-32. View in: PubMed

  181. Lee TC, Li L, Philipson L, Ziff EB. Myc represses transcription of the growth arrest gene gas1. Proc Natl Acad Sci U S A. 1997 Nov 25; 94(24):12886-91. View in: PubMed

  182. Bonini JA, Martin SK, Dralyuk F, Roe MW, Philipson LH, Steiner DF. Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3. DNA Cell Biol. 1997 Oct; 16(10):1249-56. View in: PubMed

  183. Katze MG, Persson H, Philipson L. Control of adenovirus early gene expression: posttranscriptional control mediated by both viral and cellular gene products. Mol Cell Biol. 1981 Sep; 1(9):807-13. View in: PubMed

  184. Larsson PG, Philipson L. Simulation of the influence of different factors on the motor nerve conduction velocity measurement. Part 2: Pathological conditions. Electromyogr Clin Neurophysiol. 1997 Jun-Jul; 37(4):195-9. View in: PubMed

  185. Tomko RP, Xu R, Philipson L. HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses. Proc Natl Acad Sci U S A. 1997 Apr 01; 94(7):3352-6. View in: PubMed

  186. Marubio LM, Röenfeld M, Dasgupta S, Miller RJ, Philipson LH. Isoform expression of the voltage-dependent calcium channel alpha 1E. Recept Channels. 1996; 4(4):243-51. View in: PubMed

  187. Roe MW, Worley JF, Mittal AA, Kuznetsov A, DasGupta S, Mertz RJ, Witherspoon SM, Blair N, Lancaster ME, McIntyre MS, Shehee WR, Dukes ID, Philipson LH. Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling. J Biol Chem. 1996 Dec 13; 271(50):32241-6. View in: PubMed

  188. Zaric D, Hallgren S, Leissner L, Nydahl PA, Adel SO, Philipson L, Samuelsson L, Leissner P, Axelsson K. Evaluation of epidural sensory block by thermal stimulation, laser stimulation, and recording of somatosensory evoked potentials. Reg Anesth. 1996 Mar-Apr; 21(2):124-38. View in: PubMed

  189. Zaric D, Nydahl PA, Philipson L, Samuelsson L, Heierson A, Axelsson K. The effect of continuous lumbar epidural infusion of ropivacaine (0.1%, 0.2%, and 0.3%) and 0.25% bupivacaine on sensory and motor block in volunteers: a double-blind study. Reg Anesth. 1996 Jan-Feb; 21(1):14-25. View in: PubMed

  190. Roe MW, Worley JF, Tokuyama Y, Philipson LH, Sturis J, Tang J, Dukes ID, Bell GI, Polonsky KS. NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. Am J Physiol. 1996 Jan; 270(1 Pt 1):E133-40. View in: PubMed

  191. Toth PT, Shekter LR, Ma GH, Philipson LH, Miller RJ. Selective G-protein regulation of neuronal calcium channels. J Neurosci. 1996 Aug 01; 16(15):4617-24. View in: PubMed

  192. Dukes ID, Philipson LH. K+ channels: generating excitement in pancreatic beta-cells. Diabetes. 1996 Jul; 45(7):845-53. View in: PubMed

  193. Lee TE, Philipson LH, Nelson DJ. N-type inactivation in the mammalian Shaker K+ channel Kv1.4. J Membr Biol. 1996 Jun; 151(3):225-35. View in: PubMed

  194. Philipson LH, Eddy RL, Shows TB, Bell GI. Assignment of human potassium channel gene KCNA4 (Kv1.4, PCN2) to chromosome 11q13.4-->q14.1. Genomics. 1993 Feb; 15(2):463-4. View in: PubMed

  195. de Martin R, Strasswimmer J, Philipson L. A new luciferase promoter insertion vector for the analysis of weak transcriptional activities. Gene. 1993 Feb 14; 124(1):137-8. View in: PubMed

  196. Philipson LH, Kusnetsov A, Larson T, Zeng Y, Westermark G. Human, rodent, and canine pancreatic beta-cells express a sodium channel alpha 1-subunit related to a fetal brain isoform. Diabetes. 1993 Sep; 42(9):1372-7. View in: PubMed

  197. de Martin R, Cowled PA, Smith SE, Papavassiliou AG, Sorrentino V, Philipson L, Bohmann D. Structure and regulation of the growth arrest-specific (gas-1) promoter. J Biol Chem. 1993 Oct 25; 268(30):22788-93. View in: PubMed

  198. Barone MV, Pepperkok R, Peverali FA, Philipson L. Id proteins control growth induction in mammalian cells. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4985-8. View in: PubMed

  199. Yano H, Philipson LH, Kugler JL, Tokuyama Y, Davis EM, Le Beau MM, Nelson DJ, Bell GI, Takeda J. Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA. Mol Pharmacol. 1994 May; 45(5):854-60. View in: PubMed

  200. Holzwarth JA, Gibbons SJ, Brorson JR, Philipson LH, Miller RJ. Glutamate receptor agonists stimulate diverse calcium responses in different types of cultured rat cortical glial cells. J Neurosci. 1994 Apr; 14(4):1879-91. View in: PubMed

  201. Dukes ID, McIntyre MS, Mertz RJ, Philipson LH, Roe MW, Spencer B, Worley JF. Dependence on NADH produced during glycolysis for beta-cell glucose signaling. J Biol Chem. 1994 Apr 15; 269(15):10979-82. View in: PubMed

  202. Cowled PA, Ciccarelli C, Coccia E, Philipson L, Sorrentino V. Expression of growth arrest-specific (gas) genes in senescent murine cells. Exp Cell Res. 1994 Apr; 211(2):197-202. View in: PubMed

  203. Barone MV, Crozat A, Tabaee A, Philipson L, Ron D. CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest. Genes Dev. 1994 Feb 15; 8(4):453-64. View in: PubMed

  204. Stoffel M, Espinosa R, Powell KL, Philipson LH, Le Beau MM, Bell GI. Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism. Genomics. 1994 May 01; 21(1):254-6. View in: PubMed

  205. Williams ME, Marubio LM, Deal CR, Hans M, Brust PF, Philipson LH, Miller RJ, Johnson EC, Harpold MM, Ellis SB. Structure and functional characterization of neuronal alpha 1E calcium channel subtypes. J Biol Chem. 1994 Sep 02; 269(35):22347-57. View in: PubMed

  206. Roe MW, Philipson LH, Frangakis CJ, Kuznetsov A, Mertz RJ, Lancaster ME, Spencer B, Worley JF, Dukes ID. Defective glucose-dependent endoplasmic reticulum Ca2+ sequestration in diabetic mouse islets of Langerhans. J Biol Chem. 1994 Jul 15; 269(28):18279-82. View in: PubMed

  207. Lee TE, Philipson LH, Kuznetsov A, Nelson DJ. Structural determinant for assembly of mammalian K+ channels. Biophys J. 1994 Mar; 66(3 Pt 1):667-73. View in: PubMed

  208. Philipson LH, Rosenberg MP, Kuznetsov A, Lancaster ME, Worley JF, Roe MW, Dukes ID. Delayed rectifier K+ channel overexpression in transgenic islets and beta-cells associated with impaired glucose responsiveness. J Biol Chem. 1994 Nov 11; 269(45):27787-90. View in: PubMed

  209. Peverali FA, Ramqvist T, Saffrich R, Pepperkok R, Barone MV, Philipson L. Regulation of G1 progression by E2A and Id helix-loop-helix proteins. EMBO J. 1994 Sep 15; 13(18):4291-301. View in: PubMed

  210. Malayev AA, Nelson DJ, Philipson LH. Mechanism of clofilium block of the human Kv1.5 delayed rectifier potassium channel. Mol Pharmacol. 1995 Jan; 47(1):198-205. View in: PubMed

  211. Ma GH, Miller RJ, Kuznetsov A, Philipson LH. kappa-Opioid receptor activates an inwardly rectifying K+ channel by a G protein-linked mechanism: coexpression in Xenopus oocytes. Mol Pharmacol. 1995 May; 47(5):1035-40. View in: PubMed

  212. Philipson LH, Steiner DF. Pas de deux or more: the sulfonylurea receptor and K+ channels. Science. 1995 Apr 21; 268(5209):372-3. View in: PubMed

  213. Kletsas D, Stathakos D, Sorrentino V, Philipson L. The growth-inhibitory block of TGF-beta is located close to the G1/S border in the cell cycle. Exp Cell Res. 1995 Apr; 217(2):477-83. View in: PubMed

  214. Philipson LH, Malayev A, Kuznetsov A, Chang C, Nelson DJ. Functional and biochemical characterization of the human potassium channel Kv1.5 with a transplanted carboxyl-terminal epitope in stable mammalian cell lines. Biochim Biophys Acta. 1993 Nov 21; 1153(1):111-21. View in: PubMed

  215. Mays DJ, Foose JM, Philipson LH, Tamkun MM. Localization of the Kv1.5 K+ channel protein in explanted cardiac tissue. J Clin Invest. 1995 Jul; 96(1):282-92. View in: PubMed

  216. Philipson L. Adenovirus--an eternal archetype. Curr Top Microbiol Immunol. 1995; 199 ( Pt 1):1-24. View in: PubMed

  217. Philipson LH, Kuznetsov A, Toth PT, Murphy JF, Szabo G, Ma GH, Miller RJ. Functional expression of an epitope-tagged G protein-coupled K+ channel (GIRK1). J Biol Chem. 1995 Jun 16; 270(24):14604-10. View in: PubMed

  218. Philipson LH. ATP-sensitive K+ channels: paradigm lost, paradigm regained. Science. 1995 Nov 17; 270(5239):1159. View in: PubMed

  219. Persson H, Monstein HJ, Akusjärvi G, Philipson L. Adenovirus early gene products may control viral mRNA accumulation and translation in vivo. Cell. 1981 Feb; 23(2):485-96. View in: PubMed

  220. Persson H, Jansson M, Philipson L. Synthesis and genomic site for an adenovirus type 2 early glycoprotein. J Mol Biol. 1980 Feb 05; 136(4):375-94. View in: PubMed

  221. Coudron C, Ellis K, Philipson L, Schwartz NB. Preliminary characterization of a xylose acceptor prepared by hydrogen fluoride treatment of proteoglycan core protein. Biochem Biophys Res Commun. 1980 Jan 29; 92(2):618-23. View in: PubMed

  222. Persson H, Katze MG, Philipson L. Control of adenovirus early gene expression: accumulation of viral mRNA after infection of transformed cells. J Virol. 1981 Nov; 40(2):358-66. View in: PubMed

  223. Jörnvall H, Aleström P, Akusjärvi G, von Bahr-Lindström H, Philipson L, Pettersson U. Order of the CNBr fragments in the adenovirus hexon protein. J Biol Chem. 1981 Jun 25; 256(12):6204-12. View in: PubMed

  224. Persson H, Philipson L. Regulation of adenovirus gene expression. Curr Top Microbiol Immunol. 1982; 97:157-203. View in: PubMed

  225. Lehtovaara P, Ulmanen I, Kääriäinen L, Keränen S, Philipson L. Synthesis and processing of Semliki Forest virus-specific nonstructural proteins in vivo and in vitro. Eur J Biochem. 1980 Dec; 112(3):461-8. View in: PubMed

  226. Uhlén M, Svensson C, Josephson S, Aleström P, Chattapadhyaya JB, Pettersson U, Philipson L. Leader arrangement in the adenovirus fiber mRNA. EMBO J. 1982; 1(2):249-54. View in: PubMed

  227. Katze MG, Persson H, Johansson BM, Philipson L. Control of adenovirus gene expression: cellular gene products restrict expression of adenovirus host range mutants in nonpermissive cells. J Virol. 1983 Apr; 46(1):50-9. View in: PubMed

  228. Smith TJ, Murata Y, Horwitz AL, Philipson L, Refetoff S. Regulation of glycosaminoglycan synthesis by thyroid hormone in vitro. J Clin Invest. 1982 Nov; 70(5):1066-73. View in: PubMed

  229. Weber J, Philipson L. Protein composition of adenovirus nucleoprotein complexes extracted from infected cells. Virology. 1984 Jul 30; 136(2):321-7. View in: PubMed

  230. Philipson LH, Schwartz NB. Subcellular localization of hyaluronate synthetase in oligodendroglioma cells. J Biol Chem. 1984 Apr 25; 259(8):5017-23. View in: PubMed

  231. Löfdahl S, Guss B, Uhlén M, Philipson L, Lindberg M. Gene for staphylococcal protein A. Proc Natl Acad Sci U S A. 1983 Feb; 80(3):697-701. View in: PubMed

  232. Uhlén M, Guss B, Nilsson B, Gatenbeck S, Philipson L, Lindberg M. Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications. J Biol Chem. 1984 Feb 10; 259(3):1695-702. View in: PubMed

  233. Nilsson B, Uhlén M, Josephson S, Gatenbeck S, Philipson L. An improved positive selection plasmid vector constructed by oligonucleotide mediated mutagenesis. Nucleic Acids Res. 1983 Nov 25; 11(22):8019-30. View in: PubMed

  234. Pettersson RF, Lundström K, Chattopadhyaya JB, Josephson S, Philipson L, Kääriäinen L, Palva I. Chemical synthesis and molecular cloning of a STOP oligonucleotide encoding an UGA translation terminator in all three reading frames. Gene. 1983 Sep; 24(1):15-27. View in: PubMed

  235. Jansson M, Philipson L, Vennström B. Isolation and characterization of multiple human genes homologous to the oncogenes of avian erythroblastosis virus. EMBO J. 1983; 2(4):561-5. View in: PubMed

  236. Stålhandske P, Persson H, Perricaudet M, Philipson L, Pettersson U. Structure of three spliced mRNAs from region E3 of adenovirus type 2. Gene. 1983 May-Jun; 22(2-3):157-65. View in: PubMed

  237. Pfeifer S, Zabielski J, Ohlsson R, Frykberg L, Knowles J, Pettersson R, Oker-Blom N, Philipson L, Vaheri A, Vennström B. Avian acute leukemia virus OK 10: analysis of its myc oncogene by molecular cloning. J Virol. 1983 May; 46(2):347-54. View in: PubMed

  238. van Eekelen C, Ohlsson R, Philipson L, Mariman E, van Beek R, van Venrooij W. Sequence dependent interaction of hnRNP proteins with late adenoviral transcripts. Nucleic Acids Res. 1982 Nov 25; 10(22):7115-31. View in: PubMed

  239. Signäs C, Katze MG, Persson H, Philipson L. An adenovirus glycoprotein binds heavy chains of class I transplantation antigens from man and mouse. Nature. 1982 Sep 09; 299(5879):175-8. View in: PubMed

  240. Ohlsson RI, van Eekelen C, Philipson L. Non-random localization of ribonucleoprotein (RNP) structures within an adenovirus mRNA precursor. Nucleic Acids Res. 1982 May 25; 10(10):3053-68. View in: PubMed

  241. Monstein HJ, Philipson L. The conformation of adenovirus VAI-RNA in solution. Nucleic Acids Res. 1981 Sep 11; 9(17):4239-50. View in: PubMed

  242. Jörnvall H, Akusjärvi G, Aleström P, von Bahr-Lindström H, Pettersson U, Appella E, Fowler AV, Philipson L. The adenovirus hexon protein. The primary structure of the polypeptide and its correlation with the hexon gene. J Biol Chem. 1981 Jun 25; 256(12):6181-6. View in: PubMed

  243. Löfdahl S, Sjöström JE, Philipson L. Cloning of restriction fragments of DNA from staphylococcal bacteriophage phi 11. J Virol. 1981 Feb; 37(2):795-801. View in: PubMed

  244. Linné T, Philipson L. Further characterization of the phosphate moiety of the adenovirus type 2 DNA-binding protein. Eur J Biochem. 1980 Jan; 103(2):259-70. View in: PubMed

  245. Monstein HJ, Westin G, Philipson L, Pettersson U. A candidate gene for human U1 RNA. EMBO J. 1982; 1(1):133-7. View in: PubMed

  246. Monstein HJ, Hammarström K, Westin G, Zabielski J, Philipson L, Pettersson U. Loci for human U1 RNA: structural and evolutionary implications. J Mol Biol. 1983 Jun 25; 167(2):245-57. View in: PubMed

  247. Reichel R, Monstein HJ, Jansen HW, Philipson L, Benecke BJ. Small nuclear RNAs are encoded in the nontranscribed region of ribosomal spacer DNA. Proc Natl Acad Sci U S A. 1982 May; 79(10):3106-10. View in: PubMed

  248. van Eekelen C, Buijtels H, Linné T, Ohlsson R, Philipson L, van Venrooij W. Detection of a cellular polypeptide associated with adenovirus-coded VA RNA using in vitro labeling of proteins cross-linked to RNA. Nucleic Acids Res. 1982 May 25; 10(10):3039-52. View in: PubMed

  249. Westin G, Monstein HJ, Zabielski J, Philipson L, Pettersson U. Human DNA sequences complementary to the small nuclear RNA U2. Nucleic Acids Res. 1981 Dec 11; 9(23):6323-38. View in: PubMed

  250. Nilsson G, Philipson L. Cell growth inhibition of human cell lines by human tissue extracts. Exp Cell Res. 1968 Aug-Sep; 51(2-3):275-90. View in: PubMed

  251. Philipson L, Wall R, Glickman G, Darnell JE. Addition of polyadenylate sequences to virus-specific RNA during adenovirus replication. Proc Natl Acad Sci U S A. 1971 Nov; 68(11):2806-9. View in: PubMed

  252. Fridborg K, Hjertén S, Höglund S, Liljas A, Lundberg BK, Oxelfelt P, Philipson L, Strandberg B. Purification, electron microscopy, and x-ray diffraction studies of the satellite tobacco necrosis virus. Proc Natl Acad Sci U S A. 1965 Aug; 54(2):513-21. View in: PubMed

  253. Darnell JE, Philipson L, Wall R, Adesnik M. Polyadenylic acid sequences: role in conversion of nuclear RNA into messenger RNA. Science. 1971 Oct 29; 174(4008):507-10. View in: PubMed

  254. Wall R, Philipson L, Darnell JE. Processing of adenovirus specific nuclear RNA during virus replication. Virology. 1972 Oct; 50(1):27-34. View in: PubMed

  255. Everitt E, Sundquist B, Philipson L. Mechanism of the arginine requirement for adenovirus synthesis. I. Synthesis of structural proteins. J Virol. 1971 Nov; 8(5):742-53. View in: PubMed

  256. Lonberg-Holm K, Philipson L. Early events of virus-cell interaction in an adenovirus system. J Virol. 1969 Oct; 4(4):323-38. View in: PubMed

  257. Jörnvall H, Ohlsson H, Philipson L. An acetylated N-terminus of adenovirus type 2 hexon protein. Biochem Biophys Res Commun. 1974 Jan 23; 56(2):304-10. View in: PubMed

  258. Philipson L, Lindberg U, Persson T, Vennström B. Transcription and processing of viral messenger RNA in mammalian cells. Hoppe Seylers Z Physiol Chem. 1973 Jun; 354(6):594-5. View in: PubMed

  259. Doerfler W, Lundholm U, Rensing U, Philipson L. Intracellular forms of Adenovirus DNA. II. Isolation in dye-buoyant density gradients of a DNA-RNA complex from KB cells infected with Adenovirus type 2. J Virol. 1973 Oct; 12(4):793-807. View in: PubMed

  260. Lindberg U, Persson T, Philipson L. Isolation and characterization of adenovirus messenger ribonucleic acid in productive infection. J Virol. 1972 Nov; 10(5):909-19. View in: PubMed

  261. Pettersson U, Philipson L. Synthesis of complementary RNA sequences during productive adenovirus infection. Proc Natl Acad Sci U S A. 1974 Dec; 71(12):4887-91. View in: PubMed

  262. Rydén AC, Lindberg M, Philipson L. Isolation and characterization of two protease-producing mutants from Staphylococcus aureus. J Bacteriol. 1973 Oct; 116(1):25-32. View in: PubMed

  263. Oberg B, Philipson L. Binding of histidine to tobacco mosaic virus RNA. Biochem Biophys Res Commun. 1972 Aug 21; 48(4):927-32. View in: PubMed

  264. Crowell RL, Philipson L. Specific alterations of coxsackievirus B3 eluted from HeLa cells. J Virol. 1971 Oct; 8(4):509-15. View in: PubMed

  265. Brishammar S, Philipson L. Purification and properties of a non-specific hemagglutination inhibitor from human serum against picornaviruses. Biochim Biophys Acta. 1966 Sep 26; 127(1):140-50. View in: PubMed

  266. Jelinek W, Adesnik M, Salditt M, Sheiness D, Wall R, Molloy G, Philipson L, Darnell JE. Further evidence on the nuclear origin and transfer to the cytoplasm of polyadenylic acid sequences in mammalian cell RNA. J Mol Biol. 1973 Apr 15; 75(3):515-32. View in: PubMed

  267. Philipson LH, Westley J, Schwartz NB. Effect of hyaluronidase treatment of intact cells on hyaluronate synthetase activity. Biochemistry. 1985 Dec 31; 24(27):7899-906. View in: PubMed

  268. Schwartz NB, Habib G, Campbell S, D'Elvlyn D, Gartner M, Krueger R, Olson C, Philipson L. Synthesis and structure of proteoglycan core protein. Fed Proc. 1985 Feb; 44(2):369-72. View in: PubMed

  269. Nilsson B, Holmgren E, Josephson S, Gatenbeck S, Philipson L, Uhlen M. Efficient secretion and purification of human insulin-like growth factor I with a gene fusion vector in Staphylococci. Nucleic Acids Res. 1985 Feb 25; 13(4):1151-62. View in: PubMed

  270. Paulssen EJ, Aleström P, Johansen BT, Kriz M, Philipson L, Gautvik KM. Novel prolactin related mRNAs in rat pituitary cells. Biochem Biophys Res Commun. 1986 Aug 14; 138(3):1015-22. View in: PubMed

  271. Löwenadler B, Jansson B, Paleus S, Holmgren E, Nilsson B, Moks T, Palm G, Josephson S, Philipson L, Uhlén M. A gene fusion system for generating antibodies against short peptides. Gene. 1987; 58(1):87-97. View in: PubMed

  272. Philipson L, Sörbye R. Control accuracy and response time in multiple-state myoelectric control of upper-limb prostheses. Initial results in nondisabled volunteers. Med Biol Eng Comput. 1987 May; 25(3):289-93. View in: PubMed

  273. Schneider C, King RM, Philipson L. Genes specifically expressed at growth arrest of mammalian cells. Cell. 1988 Sep 09; 54(6):787-93. View in: PubMed

  274. Stunnenberg HG, Lange H, Philipson L, van Miltenburg RT, van der Vliet PC. High expression of functional adenovirus DNA polymerase and precursor terminal protein using recombinant vaccinia virus. Nucleic Acids Res. 1988 Mar 25; 16(6):2431-44. View in: PubMed

  275. Soll D, Kirschstein RL, Philipson L, Uchida H. DNA databases monitored. Science. 1988 Apr 22; 240(4851):375. View in: PubMed

  276. Philipson L. The DNA data libraries. Nature. 1988 Apr 21; 332(6166):676. View in: PubMed

  277. Philipson L. Gene technology at the threshold of clinical applications. Introduction to the subject. Arzneimittelforschung. 1988 Mar; 38(3A):431-2. View in: PubMed

  278. Löwenadler B, Nilsson B, Abrahmsén L, Moks T, Ljungqvist L, Holmgren E, Paleus S, Josephson S, Philipson L, Uhlén M. Production of specific antibodies against protein A fusion proteins. EMBO J. 1986 Sep; 5(9):2393-8. View in: PubMed

  279. Philipson L. Positive and negative control of carcinogenesis. Eur J Haematol. 1988 Oct; 41(4):305-16. View in: PubMed

  280. Ciliberto G, Palla F, Tebb G, Mattaj IW, Philipson L. Properties of a U1 RNA enhancer-like sequence. Nucleic Acids Res. 1987 Mar 25; 15(6):2403-16. View in: PubMed

  281. Theissen H, Etzerodt M, Reuter R, Schneider C, Lottspeich F, Argos P, Lührmann R, Philipson L. Cloning of the human cDNA for the U1 RNA-associated 70K protein. EMBO J. 1986 Dec 01; 5(12):3209-17. View in: PubMed

  282. Ciliberto G, Dathan N, Frank R, Philipson L, Mattaj IW. Formation of the 3' end on U snRNAs requires at least three sequence elements. EMBO J. 1986 Nov; 5(11):2931-7. View in: PubMed

  283. Lehrach H, Frischauf AM, Philipson L. Molecular tools for the mapping of the human genome. Prog Clin Biol Res. 1985; 177:7-15. View in: PubMed

  284. Schickedanz J, Philipson L, Ansorge W, Pepperkok R, Klein R, Koszinowski UH. The 89,000-Mr murine cytomegalovirus immediate-early protein stimulates c-fos expression and cellular DNA synthesis. J Virol. 1988 Sep; 62(9):3341-7. View in: PubMed

  285. Dreyfuss G, Philipson L, Mattaj IW. Ribonucleoprotein particles in cellular processes. J Cell Biol. 1988 May; 106(5):1419-25. View in: PubMed

  286. Cameron G, Kahn P, Philipson L. Journals and databanks. Nature. 1989 Dec 21-28; 342(6252):848. View in: PubMed

  287. Etzerodt M, Vignali R, Ciliberto G, Scherly D, Mattaj IW, Philipson L. Structure and expression of a Xenopus gene encoding an snRNP protein (U1 70K). EMBO J. 1988 Dec 20; 7(13):4311-21. View in: PubMed

  288. Pepperkok R, Schneider C, Philipson L, Ansorge W. Single cell assay with an automated capillary microinjection system. Exp Cell Res. 1988 Oct; 178(2):369-76. View in: PubMed

  289. Pepperkok R, Zanetti M, King R, Delia D, Ansorge W, Philipson L, Schneider C. Automatic microinjection system facilitates detection of growth inhibitory mRNA. Proc Natl Acad Sci U S A. 1988 Sep; 85(18):6748-52. View in: PubMed

  290. Ciliberto G, Buckland R, Cortese R, Philipson L. Transcription signals in embryonic Xenopus laevis U1 RNA genes. EMBO J. 1985 Jun; 4(6):1537-43. View in: PubMed

  291. Sorrentino V, Pepperkok R, Davis RL, Ansorge W, Philipson L. Cell proliferation inhibited by MyoD1 independently of myogenic differentiation. Nature. 1990 Jun 28; 345(6278):813-5. View in: PubMed

  292. Philipson LH, Schaefer K, LaMendola J, Bell GI, Steiner DF. Sequence of a human fetal skeletal muscle potassium channel cDNA related to RCK4. Nucleic Acids Res. 1990 Dec 11; 18(23):7160. View in: PubMed

  293. de Martin R, Philipson L. The gene for cyclophilin (peptidyl-prolyl cis-trans isomerase) from Schizosaccharomyces pombe. Nucleic Acids Res. 1990 Aug 25; 18(16):4917. View in: PubMed

  294. Philipson L. Turmoil in European biology. Nature. 1991 May 09; 351(6322):91-2. View in: PubMed

  295. Philipson LH, Hice RE, Schaefer K, LaMendola J, Bell GI, Nelson DJ, Steiner DF. Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel. Proc Natl Acad Sci U S A. 1991 Jan 01; 88(1):53-7. View in: PubMed

  296. Kallin B, de Martin R, Etzold T, Sorrentino V, Philipson L. Cloning of a growth arrest-specific and transforming growth factor beta-regulated gene, TI 1, from an epithelial cell line. Mol Cell Biol. 1991 Oct; 11(10):5338-45. View in: PubMed

  297. Sibbald PR, Philipson L, Cameron G. Consistent policy? Nature. 1992 Jan 09; 355(6356):103. View in: PubMed

  298. Manfioletti G, Ruaro ME, Del Sal G, Philipson L, Schneider C. A growth arrest-specific (gas) gene codes for a membrane protein. Mol Cell Biol. 1990 Jun; 10(6):2924-30. View in: PubMed

  299. Ciccarelli C, Philipson L, Sorrentino V. Regulation of expression of growth arrest-specific genes in mouse fibroblasts. Mol Cell Biol. 1990 Apr; 10(4):1525-9. View in: PubMed

  300. Coccia EM, Cicala C, Charlesworth A, Ciccarelli C, Rossi GB, Philipson L, Sorrentino V. Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development. Mol Cell Biol. 1992 Aug; 12(8):3514-21. View in: PubMed

  301. Philipson L. Integration of European life sciences. Science. 1992 Apr 24; 256(5056):478. View in: PubMed

  302. Philipson LH, Miller RJ. A small K+ channel looms large. Trends Pharmacol Sci. 1992 Jan; 13(1):8-11. View in: PubMed

  303. Del Sal G, Ruaro ME, Philipson L, Schneider C. The growth arrest-specific gene, gas1, is involved in growth suppression. Cell. 1992 Aug 21; 70(4):595-607. View in: PubMed

  304. Pepperkok R, Schneider C, Philipson L, Ansorge W. Single cell assay with an automated capillary microinjection system. Cytotechnology. 1991; 5 Suppl 1:93-8. View in: PubMed

  305. Pettersson U, Tibbetts C, Philipson L. Hybridization maps of early and late messenger RNA sequences on the adenovirus type 2 genome. J Mol Biol. 1976 Mar 15; 101(4):479-501. View in: PubMed

  306. Philipson L, Pettersson U, Lindberg U, Tibbetts C, Vennström B, Persson T. RNA synthesis and processing in adenovirus-infected cells. Cold Spring Harb Symp Quant Biol. 1975; 39 Pt 1:447-56. View in: PubMed

  307. Söderlund H, Pettersson U, Vennström B, Philipson L, Mathews MB. A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2. Cell. 1976 Apr; 7(4):585-93. View in: PubMed

  308. Philipson L. Adenovirus gene expression-a model for mammalian cells. FEBS Lett. 1977 Mar 01; 74(2):167-73. View in: PubMed

  309. Everitt E, Lutter L, Philipson L. Structural proteins of adenoviruses. XII. Location and neighbor relationship among proteins of adenovirion type 2 as revealed by enzymatic iodination, immunoprecipitation and chemical cross-linking. Virology. 1975 Sep; 67(1):197-208. View in: PubMed

  310. Oberg B, Saborio J, Persson T, Everitt E, Philipson L. Identification of the in vitro translation products of adenovirus mRNA by immunoprecipitation. J Virol. 1975 Jan; 15(1):199-207. View in: PubMed

  311. Forsblom S, Rigler R, Ehrenberg M, Philipson L. Kinetic studies on the cleavage of adenovirus DNA by restriction endonuclease Eco RI. Nucleic Acids Res. 1976 Dec; 3(12):3255-69. View in: PubMed

  312. Persson H, Oberg B, Philipson L. Purification and characterization of an early protein (E14K) from adenovirus type 2-infected cells. J Virol. 1978 Oct; 28(1):119-39. View in: PubMed

  313. Vennström B, Pettersson U, Philipson L. Initiation of transcription in nuclei isolated from adenovirus infected cells. Nucleic Acids Res. 1978 Jan; 5(1):205-19. View in: PubMed

  314. Vennström B, Pettersson U, Philipson L. Two initiation sites for adenovirus 5.5S RNA. Nucleic Acids Res. 1978 Jan; 5(1):195-204. View in: PubMed

  315. Edvardsson B, Ustacelebi S, Williams J, Philipson L. Assembly intermediates among adenovirus type 5 temperature-sensitive mutants. J Virol. 1978 Feb; 25(2):641-51. View in: PubMed

  316. Philipson L, Tiollais P. Rational containment on recombinant DNA. Nature. 1977 Jul 14; 268(5616):90-1. View in: PubMed

  317. Johansson K, Persson H, Lewis AM, Pettersson U, Tibbetts C, Philipson L. Viral DNA sequences and gene products in hamster cells transformed by adenovirus type 2. J Virol. 1978 Sep; 27(3):628-39. View in: PubMed

  318. Johansson K, Pettersson U, Philipson L, Tibbetts C. Reassociation of complementary strand-specific adenovirus type 2 DNA with viral DNA sequences of transformed cells. J Virol. 1977 Jul; 23(1):29-35. View in: PubMed

  319. Vennström B, Persson H, Pettersson U, Philipson L. A DRB (5,6 dichloro-beta-D-ribofuranosylbenzimidazole)-resistant adenovirus mRNA. Nucleic Acids Res. 1979 Nov 24; 7(6):1405-18. View in: PubMed

  320. Persson H, Perricaudet M, Tolun A, Philipson L, Pettersson U. Purification of RNA-DNA hybrids by exclusion chromatography. J Biol Chem. 1979 Aug 25; 254(16):7999-8003. View in: PubMed

  321. Tate VE, Philipson L. Parental adenovirus DNA accumulates in nucleosome-like structures in infected cells. Nucleic Acids Res. 1979 Jun 25; 6(8):2769-85. View in: PubMed

  322. Persson H, Signäs C, Philipson L. Purification and characterization of an early glycoprotein from adenovirus type 2-infected cells. J Virol. 1979 Mar; 29(3):938-48. View in: PubMed

  323. Linné T, Jörnvall H, Philipson L. Purification and characterization of the phosphorylated DNA-binding protein from adenovirus-type-2-infected cells. Eur J Biochem. 1977 Jun 15; 76(2):481-90. View in: PubMed

  324. Perricaudet M, Fritsch A, Pettersson U, Philipson L, Tiollais P. Excision and recombination of adenovirus DNA fragments in Escherichia coli. Science. 1977 Apr 08; 196(4286):208-10. View in: PubMed

  325. Kvist S, Ostberg L, Persson H, Philipson L, Peterson PA. Molecular association between transplantation antigens and cell surface antigen in adenovirus-transformed cell line. Proc Natl Acad Sci U S A. 1978 Nov; 75(11):5674-8. View in: PubMed

  326. Lonberg-Holm K, Crowell RL, Philipson L. Unrelated animal viruses share receptors. Nature. 1976 Feb 26; 259(5545):679-81. View in: PubMed

  327. Philipson L, Pettersson U, Lindberg U. Molecular biology of adenoviruses. Virol Monogr. 1975; 14:1-115. View in: PubMed

  328. Mak S, Oberg B, Johansson K, Philipson L. Purification of adenovirus messenger ribonucleic acid by an aqueous polymer two-phase system. Biochemistry. 1976 Dec 28; 15(26):5754-61. View in: PubMed