12-Lipoxygenase Inhibition Improves Glycemia and Obesity-associated Inflammation in Male Human Gene Replacement Mice.
12-Lipoxygenase Inhibition Improves Glycemia and Obesity-associated Inflammation in Male Human Gene Replacement Mice. Endocrinology. 2025 Apr 22; 166(6).
PMID: 40186458
Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function.
Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function. J Biol Chem. 2025 Feb; 301(2):108209.
PMID: 39832654
12-Lipoxygenase inhibition improves glucose homeostasis and obesity-associated inflammation in human gene replacement mice.
12-Lipoxygenase inhibition improves glucose homeostasis and obesity-associated inflammation in human gene replacement mice. bioRxiv. 2025 Jan 13.
PMID: 39868153
Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation.
Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation. J Biol Chem. 2024 01; 300(1):105561.
PMID: 38097183
Non-Alcoholic Fatty Liver Disease: Translating Disease Mechanisms into Therapeutics Using Animal Models.
Non-Alcoholic Fatty Liver Disease: Translating Disease Mechanisms into Therapeutics Using Animal Models. Int J Mol Sci. 2023 Jun 10; 24(12).
PMID: 37373143
A Novel 2-Hit Zebrafish Model to Study Early Pathogenesis of Non-Alcoholic Fatty Liver Disease.
A Novel 2-Hit Zebrafish Model to Study Early Pathogenesis of Non-Alcoholic Fatty Liver Disease. Biomedicines. 2022 Feb 17; 10(2).
PMID: 35203687
A Pilot Single Cell Analysis of the Zebrafish Embryo Cellular Responses to Uropathogenic Escherichia coli Infection.
A Pilot Single Cell Analysis of the Zebrafish Embryo Cellular Responses to Uropathogenic Escherichia coli Infection. Pathog Immun. 2022; 7(1):1-18.
PMID: 35178490
Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype.
Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype. Cell Metab. 2021 09 07; 33(9):1883-1893.e7.
PMID: 34496231
12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes.
12-Lipoxygenase governs the innate immune pathogenesis of islet inflammation and autoimmune diabetes. JCI Insight. 2021 07 22; 6(14).
PMID: 34128835
ß-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs.
ß-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs. Mol Metab. 2021 11; 53:101289.
PMID: 34246804